Prevalence of methylenetetrahydrofolate reductase C677T polymorphism in eastern Uttar Pradesh
نویسندگان
چکیده
منابع مشابه
Evaluation of the Association between the C677T Polymorphism of Methylenetetrahydrofolate Reductase Gene and Recurrent Spontaneous Abortion
Introduction: One factor known to cause thrombophilia in women with unexplained recurrent spontaneous abortion (RSA) is C677T polymorphism of methylenetetrahydrofolate reductase gene. This study aimed to determine the association between RSA and MTHFR C677T polymorphism in Iranian patients. Methods: In this case-control study, 30 patients with previous history of two or more consecutive unexpla...
متن کاملMethylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey*
Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies. The most frequently investigated genetic defect that plays a role in homocysteine metabolism is single point substitution (C to T) located on the 677th nucleotide of the methylenetet...
متن کاملMethylenetetrahydrofolate reductase C677T polymorphism and cognitive function in older women.
Homocysteine may play a causal role in cognitive decline. The authors analyzed the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T genotype, a correlate of plasma homocysteine levels, among 6,653 participants in the Study of Osteoporotic Fractures, a community-based, prospective cohort study of older women in four US states. During the years 1986-1998, the authors assessed whether the di...
متن کاملPrevalence of Methylenetetrahydrofolate Reductase C677T Polymorphism in women with Polycystic Ovary Syndrome in southeast of Iran
Background: One of the notable enzymes in the metabolism of folate is Methylenetetrahydrofolate reductase enzyme, this enzyme is necessary for some biological mechanisms. Mutations in the MTHFR gene could reduce the enzyme activity. Aim: The objective of this research was to assess the prevalence of the very general polymorphism, C677T, in females with polycystic ovary syndrome in the southeast...
متن کاملIs methylenetetrahydrofolate reductase C677T polymorphism associated with hyperuricemia?
Several epidemiological studies have examined the relationship of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with hyperuricemia. However, the results were controversial. We therefore conducted a large cross-sectional study (2,219 subjects) and an updated meta-analysis by combining previous studies (9,502 subjects) to provide more empirical evidence for the association. A...
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ژورنال
عنوان ژورنال: Indian Journal of Human Genetics
سال: 2012
ISSN: 0971-6866
DOI: 10.4103/0971-6866.96645